Paolo Ettore Porporato
Professore/Professoressa associato/a
- Dipartimento di Biotecnologie Molecolari e Scienze per la Salute
- SSD: BIO/13 - biologia applicata
- ORCID: orcid.org/0000-0001-8519-1552
Contatti
Presso
- Department of Molecular Biotechnology and Health Sciences
- Dipartimento di Biotecnologie Molecolari e Scienze per la Salute
- Corso di Laurea in Biotecnologie
- Laurea Magistrale in Medicina e Chirurgia - sede di Torino
- Master Program in Molecular Biotechnology
- Scuola Universitaria Interdipartimentale in Scienze Strategiche (SUISS)
- Ph.D. Program in Biomedical Sciences and Oncology
Curriculum vitae
Prodotti della ricerca
Tutti i miei prodotti della ricercaProdotti della ricerca selezionati
Wyart, Elisabeth, Reano, Simone, Hsu, Myriam Y, Longo, Dario Livio, Li, Mingchuan, Hirsch, Emilio, Filigheddu, Nicoletta, Ghigo, Alessandra, Riganti, Chiara, Porporato, Paolo Ettore (2018)
Metabolic Alterations in a Slow-Paced Model of Pancreatic Cancer-Induced Wasting.
https://iris.unito.it/handle/2318/1670017
Porporato, Paolo Ettore, Filigheddu, Nicoletta, Pedro, José Manuel Bravo-San, Kroemer, Guido, Galluzzi, Lorenzo (2018)
Mitochondrial metabolism and cancer.
https://iris.unito.it/handle/2318/1661659
De Santis, Maria Chiara, Porporato, Paolo Ettore, Martini, Miriam*, Morandi, Andrea (2018)
Signaling pathways regulating redox balance in cancer metabolism.
https://iris.unito.it/handle/2318/1691013
Li, Mingchuan, Sala, Valentina, De Santis, Maria Chiara, Cimino, James, Cappello, Paola, Pianca, Nicola, Di Bona, Anna, Margaria, Jean Piero, Martini, Miriam, Lazzarini, Edoardo, Pirozzi, Flora, Rossi, Luca, Franco, Irene, Bornbaum, Julia, Heger, Jacqueline, Rohrbach, Susanne, Perino, Alessia, Tocchetti, Carlo G, Lima, Braulio H F, Teixeira, Mauro M, Porporato, Paolo E, Schulz, Rainer, Angelini, Annalisa, Sandri, Marco, Ameri, Pietro, Sciarretta, Sebastiano, Lima-Júnior, Roberto César P, Mongillo, Marco, Zaglia, Tania, Morello, Fulvio, Novelli, Francesco, Hirsch, Emilio, Ghigo, Alessandra (2018)
Phosphoinositide 3-Kinase Gamma Inhibition Protects from Anthracycline Cardiotoxicity and Reduces Tumor Growth.
https://iris.unito.it/handle/2318/1662394
Bindels, Laure B , Porporato, Paolo E , Ducastel, Sarah, Sboarina, Martina, Neyrinck, Audrey M , Dewulf, Evelyne M , Feron, Olivier, Lestavel, Sophie, Cani, Patrice D , Staels, Bart, Sonveaux, Pierre, Delzenne, Nathalie M (2017)
Ffar2 expression regulates leukaemic cell growth in vivo.
https://iris.unito.it/handle/2318/1661703
Danhier, Pierre, Bański, Piotr, Payen, Valéry L, Grasso, Debora, Ippolito, Luigi, Sonveaux, Pierre, Porporato, Paolo E (2017)
Cancer metabolism in space and time: Beyond the Warburg effect.
https://iris.unito.it/handle/2318/1638236
Baldini N, De Milito A, Feron O, Gillies RJ, Michiels C, Otto AM, Pastoreková S, Pedersen SF, Porporato PE, Sonveaux P, Supuran CT, Avnet S (2017)
Annual meeting of the International Society of Cancer Metabolism (ISCaM): Metabolic networks in cancer.
https://iris.unito.it/handle/2318/1678772
Payen, Valéry L , Hsu, Myriam Y , Rädecke, Kristin S , Wyart, Elisabeth, Vazeille, Thibaut, Bouzin, Caroline, Porporato, Paolo E , Sonveaux, Pierre* (2017)
Monocarboxylate transporter MCT1 promotes tumor metastasis independently of its activity as a lactate transporter.
https://iris.unito.it/handle/2318/1661661
Contino S, Porporato PE, Bird M, Marinangeli C, Opsomer R, Sonveaux P, Bontemps F, Dewachter I, Octave JN, Bertrand L, Stanga S, Kienlen-Campard P (2017)
Presenilin 2-dependent maintenance of mitochondrial oxidative capacity and morphology.
https://iris.unito.it/handle/2318/1678774
Pérez-Escuredo, Jhudit, Dadhich, Rajesh K, Dhup, Suveera, Cacace, Andrea, Van Hée, Vincent F, De Saedeleer, Christophe J, Sboarina, Martina, Rodriguez, Fabien, Fontenille, Marie-Joséphine, Brisson, Lucie, Porporato, Paolo E, Sonveaux, Pierre (2016)
Lactate promotes glutamine uptake and metabolism in oxidative cancer cells.
https://iris.unito.it/handle/2318/1657310
Porporato, P E (2016)
Understanding cachexia as a cancer metabolism syndrome.
https://iris.unito.it/handle/2318/1657312
Avnet, S, Baldini, N, Di Pompo, G, Sonveaux, P, Zini, N, Porporato, Pe, Sboarina, M, Lemma, S (2016)
Energy metabolism in osteoclast formation and activity.
https://iris.unito.it/handle/2318/1657307
Porporato, Paolo E , Payen, Valéry L , Pérez-Escuredo, Jhudit, De Saedeleer, Christophe J , Danhier, Pierre, Copetti, Tamara, Dhup, Suveera, Tardy, Morgane, Vazeille, Thibaut, Bouzin, Caroline, Feron, Olivier, Michiels, Carine, Gallez, Bernard, Sonveaux, Pierre (2014)
A mitochondrial switch promotes tumor metastasis.
https://iris.unito.it/handle/2318/1657315
De Saedeleer, C J , Porporato, P E , Copetti, T , Pérez-Escuredo, J , Payen, V L , Brisson, L , Feron, O , Sonveaux, P (2014)
Glucose deprivation increases monocarboxylate transporter 1 (MCT1) expression and MCT1-dependent tumor cell migration.
https://iris.unito.it/handle/2318/1657316
Steinstraesser, Lars, Lam, Martin C, Jacobsen, Frank, Porporato, Paolo E, Chereddy, Kiran Kumar, Becerikli, Mustafa, Stricker, Ingo, Hancock, Robert EW, Lehnhardt, Marcus, Sonveaux, Pierre, Préat, Véronique*, Vandermeulen, Gaëlle (2014)
Skin electroporation of a plasmid encoding hCAP-18/LL-37 host defense peptide promotes wound healing.
https://iris.unito.it/handle/2318/1681346
Porporato P, Filigheddu N, Reano S, Ferrara M, Angelino E, Gnocchi V, Prodam F, Ronchi G, Fagoonee S, Fornaro M, Chianale F, Baldanzi G, Surico N, Sinigaglia F, Perroteau I, Smith R, Sun Y, Geuna S, Graziani A (2013)
Acylated and unacylated ghrelin impair skeletal muscle atrophy in mice.
https://iris.unito.it/handle/2318/132179
Porporato, Paolo E , Payen, Valéry L , De Saedeleer, Christophe J , Prã©at, Vã©ronique, Thissen, Jean-Paul, Feron, Olivier, Sonveaux, Pierre (2012)
Lactate stimulates angiogenesis and accelerates the healing of superficial and ischemic wounds in mice.
https://iris.unito.it/handle/2318/1658090
Federica Chianale, Elena Rainero, Cristina Cianflonea, Valentina Bettio, Andrea Pighini, Paolo Porporato, Nicoletta Filigheddu, Guido Serini, Fabiola Sinigaglia, Gianluca Baldanzi, Andrea Graziani (2010)
Diacylglycerol kinase α mediates HGF-induced Rac activation and membrane ruffling by regulating atypical PKC and RhoGDI.
https://iris.unito.it/handle/2318/76313
Audisio C, Raimondo S, Nicolino S, Gambarotta G, Di Scipio F, Macrì L, Montarolo F, Giacobini-Robecchi MG, Porporato P, Filigheddu N, Graziani A, Geuna S, Perroteau I (2009)
Morphological and biomolecular characterization of the neonatal olfactory bulb ensheathing cell line.
https://iris.unito.it/handle/2318/131011
Geuna S, Raimondo S, Ronchi G, Audisio C, Perroteau I, Porporato P, Filigheddu N, Graziani A (2009)
Increase in circulating des-acyl ghrelin promotes posttraumatic neural regeneration in the mouse peripheral nervous system.
https://iris.unito.it/handle/2318/70642
Rainero E , Chianale F , Porporato P , Cianflone C , Bettio V , Filigheddu N , Serini G , Graziani A (2009)
HGF induces cell migration, ruffling and Rac activation through a novel signalling pathway coupling diacylglycerol kinase alpha to PKCz/i and RhoGDI.
https://iris.unito.it/handle/2318/95638
BALDANZI G, CUTRUPI S, CHIANALE F, GNOCCHI V, RAINERO E, PORPORATO P, FILIGHEDDU N, VAN BLITTERSWIJK WJ, PAROLINI O, BUSSOLINO F, SINIGAGLIA F, GRAZIANI A (2008)
Diacylglycerol kinase-alpha phosphorylation by Src on Y335 is required for activation, membrane recruitment and Hgf-induced cell motility.
https://iris.unito.it/handle/2318/35817
FILIGHEDDU N, CUTRUPI S, PORPORATO PE, RIBONI F, BALDANZI G, CHIANALE F, FORTINA E, PIANTANIDA P, M DE BORTOLI, VACCA G, GRAZIANI A, SURICO N (2007)
Diacylglycerol Kinase is Required for HGF-induced Invasiveness and Anchorage-independent Growth of MDA-MB-231 Breast Cancer Cells.
https://iris.unito.it/handle/2318/4341
CHIANALE F, S CUTRUPI, RAINERO E, BALDANZI G, PORPORATO PE, TRAINI S, FILIGHEDDU N, GNOCCHI VF, SANTORO MM, PAROLINI O, VAN BLITTERSWIJK WJ, SINIGAGLIA, F, GRAZIANI A (2007)
Diacylglycerol Kinase-{alpha} Mediates HGF-induced Epithelial Cell Scatter by Regulating Rac Activation and Membrane Ruffling.
https://iris.unito.it/handle/2318/21544
FILIGHEDDU N, GNOCCHI VF, COSCIA M, CAPPELLI M, PORPORATO PE, TAULLI R, TRAINI S, BALDANZI G, CHIANALE F, CUTRUPI S, ARNOLETTI E, GHE C, FUBINI A, SURICO N, SINIGAGLIA F, PONZETTO C, MUCCIOLI G, CREPALDI T, GRAZIANI A (2007)
Ghrelin and Des-Acyl Ghrelin Promote Differentiation and Fusion of C2c12 Skeletal Muscle Cells.
https://iris.unito.it/handle/2318/39617
A GRAZIANI, V GNOCCHI, N FILIGHEDDU, M COSCIA, L BADA, F SOTTINI, S TRAINI, P PORPORATO, F CHIANALE, G BRIGNOLI, G BALDANZI, R TAULLI, T CREPALDI, F SINIGAGLIA (2006)
Ghrelin induces differentiation and fusion of C2C12 myoblasts and protects myotubes from atrophy.
https://iris.unito.it/handle/2318/70015
Bondi A, Valentino P, Daraio F, Porporato P, Gramaglia E, Carturan S, Gottardi E, Camaschella C, Roetto A (2005)
Hepatic expression of hemochromatosis genes in two mouse strains after phlebotomy and iron overload.
https://iris.unito.it/handle/2318/147939
Roetto A, Daraio F, Porporato P, Caruso R, Cox TM, Cazzola M, Gasparini P, Piperno A, Camaschella C (2004)
Screening hepcidin for mutations in juvenile hemochromatosis: identification of a new mutation (C70R).
https://iris.unito.it/handle/2318/147857
C Camaschella, S Bosio, M De Gobbi, G Zecchina, F Daraio, P Porporato, F Longo, A Piga, A Roetto (2003)
Rare Genetic Anemias Due to Defective Iron Recycling: Aceruloplasminemia and Type 4 Hemochromatosis.
https://iris.unito.it/handle/2318/123109
A Roetto, F Daraio, F Alberti, P Porporato, A Calì, M De Gobbi, C Camaschella (2002)
Hemochromatosis due to mutations in transferrin receptor 2.
https://iris.unito.it/handle/2318/90159
Insegnamenti
- ADE Basi biologiche e molecolari di patologie tumorali e cardiovascolari (SME1062)
Laurea Magistrale in Medicina e Chirurgia - sede di Torino - BASIS OF BIOSAFETY AND BIOSECURITY (ON LINE) (CPS0997 - MAN0706)
Scuola Universitaria Interdipartimentale in Scienze Strategiche (SUISS) - Basi biologiche (canale C) (SME0881A)
Laurea Magistrale in Medicina e Chirurgia - sede di Torino - Basi biologiche (canale D) (SME0881A)
Laurea Magistrale in Medicina e Chirurgia - sede di Torino - Basi biologiche, molecolari e di genetica umana (canale C) (SME0881)
Laurea Magistrale in Medicina e Chirurgia - sede di Torino - Basi biologiche, molecolari e di genetica umana (canale D) (SME0881)
Laurea Magistrale in Medicina e Chirurgia - sede di Torino - Cellular Biology (Sezione 1) (BIO0174C)
Corso di Laurea in Biotecnologie - Cellular Biology (Sezione 2) (BIO0174C)
Corso di Laurea in Biotecnologie - ELEMENTI DI BIOSICUREZZA (CPS0723)
Scuola Universitaria Interdipartimentale in Scienze Strategiche (SUISS) - INTEGRATED LABORATORY TECNIQUES (BIO0174)
Corso di Laurea in Biotecnologie - IN VITRO DIAGNOSTICS: PROTEOMICS, INTERACTOMICS AND METABOLOMICS (BIO0162 Pds 308-BIDD)
Master Program in Molecular Biotechnology
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